A Review on Phytochemical and Pharmacological Properties of Datura metel L.
Keywords:
Datura metel L, Solanaceae, phytocompounds, pharmacologicalAbstract
Datura metel L., commonly known as Indian thornapple, is a member of the Solanaceae family, renowned for its diverse phytochemical and pharmacological properties. The therapeutic potential of plants is attributed to their bioactive phytochemical compounds. This review explores the key constituents of Datura metel L., highlighting the presence of alkaloids such as atropine, scopolamine and hyoscyamine, along with flavonoids and terpenoids. These compounds have various pharmacological effects, including strong anticholinergic properties that are beneficial for treating motion sickness and as pre-anesthetic agents. They also exhibit sedative, analgesic, antimicrobial, anti-inflammatory and antioxidant activities. Although Datura metel L. has therapeutic potential, it carries significant toxicity risks mainly because of its alkaloids, so caution is essential when using it. This review aim at emphasizes the need for further research to standardize extracts and establish safe useful dosages, creating opportunities for innovative applications in modern medicine.
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