The effects of chloroform extract of Psoralea corylifolia seed on reproductive abilities of male albino rats
Keywords:
Aphrodisiac, Herbal medicine, Male sexual behaviour, Male rat, Psoralea corylifolia, SeedAbstract
The aim of the study is to evaluate the effect of the chloroform extract of Psoralea corylifolia on reproductive abilities of male albino rats. The chloroform extracts of P. corylifolia seeds at doses of 100, 200 and 400 mg/kg were administrated for 21 days. The sperm count of experimental animal was determined. The effect of the extract on body weight, reproductive and vital organ weight were determined. The effective chloroform extract were further studied for its effect on hormonal assay and compared with the standard reference drug sildenafil citrate. Similarly adverse effects and acute toxicity of the extract were also evaluated. Oral administration of chloroform at doses of 100, 200 and 400 mg/kg were significantly increased the sperm count in experimental animal. There was significant increase in level of testosterone in the serum with increase in the LH and FSH concentration. The extract was also observed to be devoid of any adverse effects and acute toxicity. The results of the present study demonstrate that chloroform extract of P. corylifolia seed enhance sexual behaviour in male rats. It also thus provides a rationale for the traditional use of P. corylifolia as acclaimed aphrodisiac and for the management of male sexual disorders.
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