Antioxidant and antimicrobial properties of Adhatoda vasica L. Nees

Authors

  • Wankhede TB Department of Botany, Shri Shivaji Science College, Amravati – 444604, MS, India

Keywords:

Antioxidants, antimicrobial sensitivity, pharmacology

Abstract

Plant Adhatoda vasica L. Nees (Acanthaceae) commonly known as Malabar nut is an evergreen two – three m tall shrub, sometime used as hedge, branches opposite and stem yellowish. Leaves simple, 10-20 cm long and 3 to 7.5 cm or sometime much more broad, elliptical, ovate-lanceolate, and tapering towards apex. Inflorescence terminal or sub terminal spikes, flowers white bilabiate and fruits two-valve capsule, which dehisces when mature, or dry. The plant leaves, bark and root known for traditional medicinal use in Ayurveda. The plant parts generally bitter and useful in cough, bronchitis, asthma, skin disease, eczema and scabies. The leaves extensively employed in preparations indicated in respiratory ointments and particularly in cough syrups. An antioxidant is a molecule capable of slowing or preventing the oxidation of other molecules. Oxidation is a chemical reaction that transfer electrons from a substance to oxidizing agent oxidation reaction can produce free radicals, which start chain reaction that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates and other oxidation reaction by being oxidize themselves. In present investigation preliminary antioxidants evaluated from the experimental plant and antimicrobial sensitivity test carried out against some human pathogenic microbial strains to support out the potential compounds of pharmacognostic interest.

Downloads

Download data is not yet available.

References

Anndy B, Ferreira F, Blasina C, Laftop F, Arredondo F, Dajas R and Tripathi PC (2003) Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases. Ethano pharmacol 84: 131-138.

Aviram M (2000) “Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases.” Free Radic Res 33 suppl: S85-97. PMID-11 191279.

Boyer RF, Clark HM and Laroche AP (1988) Reduction and release of ferritin iron by plant phenolics. J Inorg Biochem; 32:171-81.

Danne JL (1990) Nutrition Alwanac Mc. GRAO HLL -4445.

Havsteen B (1983) Flavonoids, a class of natural product of high pharmacological potency Biochem Pharmacol 30:1141-1148.

Hsu CY, Chao P, Hu S and Yang C (2013) "The Antioxidant and Free Radical Scavenging Activities of Chlorophylls and Pheophytins," Food and Nutrition Sciences, Vol. 4 No. 8A, 2013, pp. 1-8.

Kumar M, Dandapat S, Kumar A and Sinha MP (2014) Pharmacologiacal screening of leaf extract of Adhatoda vasica for therapeutic efficacy. Global Journal of Pharmacology Vol. 8. No. 4; 494-500.

Mamta P, Sujata B and Rachna (2013) Antioxidant activity and cytoprotective potential of ethanolic extract of Adhatoda vasica. International Journal of Pharmtech Research, Vol.5, No. 2; 501-510.

Maurya S and Singh D (2010) Quantitative analysis of total phenolic content in Adhatoda vasica Nees. extract. International Journal of Pharmtech Research, Vol.2, No. 4; 2403-2406.

Mazza G (2007) Anthocyanin and heart health ANN IST SUPERSANITA Vol. 43.No.4.369-374

Miller AL (1996) Antioxidant Flavonoids; structure function and clinical usage. Alt Med Rev 1:103-111.

NCCLS (1990) Manual on “Performance Standards for Antimicrobial Disk Susceptibility Tests”. Approved Standard NCCLS Publication, M2-A4, Villanova, PA, USA., (1990 a-b).

Pandit S, Sur K, Jana U, Debnath PK, Sen S, Bhattacharya D (2004) Prevention of carbon tetrachloride hepatotoxicity in rats by Adhatoda vasica leaves.Vol.36, No. 5: 312-313

Parekh J and Chanda S (2008) Antibacterial activity of aqueous and alcoholic extracts of 34 Indian Medicinal plants against some bacterial species. Turk. J. Biol, 32: 63-71.

Rajurkar NS, Gaikwad KN and Razavi MS (2012) Evaluation of free radicals scavenging activity of Justica adhatoda: A gamma radiation study. International Journal of Pharmacy and Pharmaceutical Sciences. Vol. 4, Suppl. 4; 93-96.

Rao KVB, Munjal M, Patnayak A, Karthik L and Kumar G (2013) Phytochemical composition, Antioxidant, Antimicrobial and Cytotoxic potential of Methanolic extract of Adhatoda vasica (Acanthaceae). Res.J. Pharm and Tech, Vol.6, No.9; 997-1002.

Rao AV and Agarwal S (2000) Role of Antioxidant Lycopene in Cancer and Heart Disease Journal of the American College of Nutrition, Vol. 19, No. 5; 563–569

Thimmaiah SR (1999) Standard Methods of Biochemical Analysis, Kalyani Publishers, Ludhiyana. ISBN 81-7663-067-5.

Ursula M, Lanfer-Marquez,, Rosa MC, Barros and Patricia Sinnecker (2005) Antioxidant activity of chlorophylls and their derivatives. Food Research International Volume 38, Issues 8–9, October–November 2005, Pages 885–891

Xianquan S, Sti J, Kakuda Y (2005) “Stability of lycopene during Food processing and storage” J Med Food 8(4) ; 413-22.

Downloads

Published

2015-06-30

How to Cite

Wankhede TB. (2015). Antioxidant and antimicrobial properties of Adhatoda vasica L. Nees. International Journal of Life Sciences, 3(2), 152–156. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/1227