NF1 gene Analysis: New paradigm by computational approach

Jadhav VA; Laeequr Raheman

Authors

Jadhav VA Department of Biophysics, D.B. College, Bhokar, Nanded, MS, India -431801, School of Life Science, SRTM University, Nanded, 431606, MS, India.
Laeequr Raheman MGM’S college of CS & IT, Nanded, 431601, MS, India

Keywords:

structure prediction, autosomal dominant, NF1, GRD

Abstract

Now a day, we are having good stimulation and regulation due to small piece of evolutionarily developed nucleotides working dynamically called gene (eg.NF1). The malfunctioning of NF1is autosomal dominant condition, contributes a set distinct genetic disorder that that cause tumors to grow along various types of nerve. In addition, it can affect the development of non-nervous tissue such as bone and skin. The NF1 gene, encodes for protein called neurofibromine, belongs to family of protein that serve as negative regulators ras oncogene. The GRD region encoded by exons 20-27a, is the function ascribed region. We are aiming to identify and analyze with structure prediction.

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References

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