Phytochemical Screening and Evaluation of Antioxidant Activity of Momordica dioica

Authors

  • Thombre Shital Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005
  • Hade Neha Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005
  • Nirmal Sakshi Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005
  • Borade Pranali Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005
  • Ingle Swati Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005
  • Pungle Rohini Department of Biotechnology, Deogiri College (Autonomous), Chhatrapati Sambhajinagar- 431005

Keywords:

Momordica dioica, fruit extract, alkaloids, phenolic compounds, antioxidant activities

Abstract

Momordica dioica is a perennial, dioecious, cucurbitaceous family commonly known as kakrol, spiny gourd.  It is used not only as preventive and curative agent for various diseases, as well as healing of health conditions like diabetes, inflammation, liver disorder, gastrointestinal conditions and reproductive problems. Momordica dioica is considered as an underutilized vegetable, although having significant presence of certain compounds containing higher nutritional value than many frequently consumed vegetables.

The Methanolic and aqueous extract of fruits of Momordica dioica was investigated for its Phytochemical properties and analysis for its active chemical ingredients. Phytochemical analysis indicated that there was presence of phenolic compounds, triterpenoids, alkaloids, glycosides in aqueous as well as methanolic extracts. The antioxidant activity of this extract was evaluated by hydrogen peroxide scavenging assay. The result indicated that methanolic extract have more antioxidant activity (86.29%) than aqueous extracts (82.9%). In the modality of incorporating both traditional use and modern scientific validation of plant-based therapeutics to build an environment of safe, effective, and cost-effective drug development.

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Published

2026-05-30

How to Cite

Thombre Shital, Hade Neha, Nirmal Sakshi, Borade Pranali, Ingle Swati, & Pungle Rohini. (2026). Phytochemical Screening and Evaluation of Antioxidant Activity of Momordica dioica. International Journal of Life Sciences, 14(1A), 41–46. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/1586

Issue

Section

Phytochemistry & Pharmacognosy