Screening of kojic acid antimicrobial activity against skin pathogens

Authors

  • Ranjit Kumar C Center of Advanced study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai-608502, Tamilnadu, India
  • Jayalakshmi S Center of Advanced study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai-608502, Tamilnadu, India

Abstract

The antibacterial and antifungal activity of kojic acid was evaluated against medically important skin pathogens. Tube Dilution Assay was used for analyzing of kojic acid minimum inhibitory concentrations (MIC), it was varied from 64 g/ml to 128 g/ml. There was no bacterial growth was appeared at MIC 64 g/ml. Kojic acid inhibited the Trychophyton rubrum MTCC296 and Candidus albicans MTCC3018 growth at MIC 128 g/ml. Disc diffusion method was chosen to elucidate the antimicrobial activity of the kojic acid. Kojic acid inhibitory zone observed was 17 mm, 14 mm, 12 mm and 9 mm, respectively against Pseudomonas aeruginosa MTCC1688, Trychophyton rubrum MTCC296, Streptococcus pyogenes MTCC1924, Candidus albicans MTCC3018, respectively. Key words: Kojic acid, Antimicrobial activity, Trichophyton rubrum, Candida albicans, Pseudomonas aeruginosa and Streptococcus pyogenes

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Published

2018-09-28

How to Cite

Ranjit Kumar C, & Jayalakshmi S. (2018). Screening of kojic acid antimicrobial activity against skin pathogens. International Journal of Life Sciences, 6(3), 755–760. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/160

Issue

Vol. 6 No. 3 (2018): International Journal of Life Sciences

Section

Research Articles

License

Copyright (c) 2018 Ranjit Kumar C, Jayalakshmi S

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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