Phytochemical screening and evaluation of In-vitro antimicrobial properties of Mentha piperita L.
Keywords:
Phytochemical, Antimicrobial, Mint, ExtractsAbstract
The present study was aimed to evaluate the phytochemical potential of hexane, acetone, chloroform, ethanol and aqueous extracts of Mentha piperita L. leaves. For the experiment, leaves of Mentha piperita L. were collected from the region of Nanded (MS), India and authenticated. The leaves of Mentha piperita L. showed the presence of alkaloids, flavonoids, tannins, phenols, saponins, steroids, terpenoids, proteins and carbohydrates. Acetone and aqueous extracts were observed to be more potent with presence of the entire screened phytochemicals. Acetone and Aqueous extract of plants show maximum content of phenols and flavonoids respectively. Also, the overall extracts showed high antimicrobial response specially acetone and chloroform extract against bacteria while in case of fungi, it showed very least response. These Phytochemical compounds are also known as plant secondary metabolites and are reported to have many biological and medicinal properties. Hence this species is expected to have many therapeutic uses and can be further studied for the production of pharmaceutical drugs.
Downloads
References
Basheer A Al-Sum, Abdullah A Al-Arfaj (2013) Antimicrobial activity of the aqueous extract of mint plant. Sci J Clin Med; 2:110-3.
Burt S (2004) Essential oils: their antibacterial properties and potential application in food. Journal of Applied Microbiology 94: 223-253.
Chang C, Yang M, Wen H, Chern J (2002) Estimation of total flavonoid content in Propolis by two complementary colorimetric methods. J Food Drug Anal. 10: 178-82.
Clark RK, Menory RC (1980) Environmental effects or peppermint (Mentha piperita). Aust J Plant Physiol; 7:685-92.
Firdaus J, Rubina L, Kumar V and M Junaid (2011) Evaluation of antimicrobial activity of plant extracts on antibiotic susceptible and resistant Staphylococcus aureus strains. J. Chem. Pharm. Res., 3(4): 777-789.
Goossens H, Ferech M, Vander Stichele R, Elseviers M (2005) Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet Group Esac Project 365:579-587.
Gulluce M, Sahin F, Sokmen M, Ozer H, Daferara D, Sokmen A, Polissiou M, Adiguzel A, Ozkan H (2007) Antimicrobial and antioxidant properties of the essential oils and methanol extract from Mentha longifolia L. ssp. longifolia. Food Chem., 104(4): 1449-1456.
Harborne AJ (1973) Phytochemical methods: a guide to modern technique of plant analysis. New York: Chapman Hall.
Hawkey PM, Jones AM (2009) The changing epidemiology of resistance. J. Antimicrob. Chemother. 64:3–10.
Kamal AM, Chowdhury KAA, Shill LK, Hossain MR, Islam N and Anaytulla IA. (2015). Phytochemical screening, cytotoxic and thrombolytic activity of extract of Brassica oleracea flower (cauliflower). Global Journal of Pharmacology. 9: 115-20.
Kirethekar Basu I (1985) Indian Medicinal Plants; 1985. p. 714-6.
Kordali S, Kotan R, Mavi A, Cakir A, Ala A and Yildirim A (2005) Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A dracunculus, Artemisia santonicum and Artemisia spicigera essential oils. Journal of Agricultural and Food Chemistry 53: 9452-9458.
Lakshmi DS and Shalini JV (2016) In-vitro antioxidant studies of fresh Brassica oleracea and the characterization of its bioactive compounds using Fourier transform infrared spectroscopy (FTIR). Journal of Chemical and Pharmaceutical Research. 8(5): 900-05.
Rasooli I (2008) Dental Biofilm prevention by Mentha spicata and Eucalyptus camaldulensis essential oils. Int. J. Infect. Dis., 12(1): 167.
Ratty AK, Das NP (1988) Effects of flavonoids on nonenzymatic lipid peroxidation: structure-activity relationship. Biochem Med Metab Biol. 39(1): 69-79.
Sameeh MY, Mohamed AA and Elazzazy AM (2016) Polyphenolic contents and antimicrobial activity of different extracts of Padina boryana Thivy and Enteromorphasp marine algae. Journal of Applied Pharmaceutical Science. 6(9): 87-92.
Singh KL, Singh LR, Devi PG, Devi NR, Singh LS and Bag GC (2013) Comparative study of phytochemical constituents and total phenolic content in the extracts of three different species of genus Hedychium. Int J Pharm Tech Res. 5(2): 601-06
Singh T, Kasture SB, Mohanty PK, Jaliwala Y, Karchuli MS. (2011) In -Vitro antioxidative activity of phenolic and flavonoid compounds extracted from fruit of Garcinia indica. Int J pharma life sci. 2(3): 613-6.
Tumah H (2005) Fourth-generation cephalosporins: in vitro activity against nosocomial Gram-negative bacilli compared with beta-lactam antibiotics and ciprofloxacin. Chemotherapy; 51:80-5.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Sontakke KS, Shinde SL
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license unless indicated otherwise in a credit line to the material. If the material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/ licenses/by/4.0/