To study the incidence and control of Candida albicans, in immune compromised individuals

Authors

  • Nikita Naik Dr Homi Bhabha State University
  • Deepa Hirani Department of Microbiology, Elphinstone College, Mumbai

Keywords:

Opportunistic pathogen, immune-compromised host

Abstract

Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections, Candidal onychomycosis, an infection of the nail plate in humans. Systemic fungal infections (fungemia) including those by C. albicans have emerged as important causes of morbidity and mortality in immune compromised patients (e.g., AIDS, cancer chemotherapy, organ or bone marrow transplantation. C.albicans biofilms may form on the surface of implantable medical devices. In addition, hospital-acquired infections by C. albicans have become a cause of major health concerns.

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References

Barelle CJ, Pries CL, MacCallum DM, Gow NA, Odds FC & Brown AJ (2006) Niche-specific regulation of central metabolic pathways in a fungal pathogen. Cell Microbiol.; 8: 961-971

Hajjeh RA, Sofair AN Harrison LH, Lyon GM, Arthington-Skaggs BA, Mirza SA, Phelan M, Morgan J, Lee-Yang W, Ciblak MA,Benjamin LE, Thompson Sanza L, Huie S, Yeo SF, Brandt ME and Warnock DW (2004) Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program. J. Clin. Microbiol. 42:1519-1527.

Pfaller MA, Diekema DJ, Messer SA, Boyken L, Hollis RJ and Jones RN (2004) In vitro susceptibilities of rare Candida bloodstream isolates to ravuconazole and three comparative antifungal agents. Diagn. Microbiol. Infect. Dis. 48:101-105.

Mathew BP and Nath M (2009), Recent approaches to antifungal therapy for invasive mycoses. ChemMedChem. Mar; 4(3):310-23.

Giri S and Kindo AJ (2014) Evaluation of antifungal susceptibility testing in Candida isolates by Candifast and disk-diffusion method. Indian J Pathol Microbiol. 2014 Oct-Dec;57(4):595-7.

Arendrup MC (2013) Candida and candidaemia. Susceptibility and epidemiology. Dan Med J. Nov;60(11): B4698.

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Published

2019-12-30

How to Cite

Nikita Naik, & Deepa Hirani. (2019). To study the incidence and control of Candida albicans, in immune compromised individuals. International Journal of Life Sciences, 7(4), 705–709. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/316

Issue

Vol. 7 No. 4 (2019): International Journal of Life Sciences

Section

Research Articles

License

Copyright (c) 2019 Nikita Naik, Deepa Hirani

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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