TLC analysis of plant alkaloid (Strychnine) in toxic baits using novel solvent system
Keywords:
Strychnine, Toxic baits, Pesticide, Thin Layer ChromatographyAbstract
Strychnine is obtained from the seeds of Strychnosnux vomica. It is an Indian origin plant and the seeds of nux-vomica are readily available in villages and often used for malicious purposes. Strychnine is highly toxic to the human as well as animals. It is used as indoor and outdoor pesticide specifically for the control of rats, gophers and moles. It is recommended for underground use. A complete and systematic detection of poisons is carried out by Forensic toxicologist. Nowadays sensitive instrumental techniques are available for detection of poisons but at the same time these techniques are more expensive and need sophisticated laboratory infrastructure. Therefore simple, cost effective and rapid thin layer chromatography method is the choice of most analysts for the screening of poisons. In this study, solvent system was developed for analysis of strychnine using Thin Layer Chromatography. This method was also applied to identify the strychnine in toxic baits using novel solvent system which will be useful for detection of strychnine in animal poisoning cases.
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