Xanthine oxidase inhibition by using different extracts of selected medicinal plants

Authors

  • Dhole GA Department of Botany, Yeshwant Mahavidyalaya, Nanded-431802, Nanded, Maharashtra State, India
  • Bodke SS Department of Botany, Yeshwant Mahavidyalaya, Nanded-431802, Nanded, Maharashtra State, India

Keywords:

Pergularia daemia, Cissus quadrangularis, Xanthine oxidase, Enzyme inhibition, arthritis, total phenolic content

Abstract

The inhibition of xanthine oxidase by various solvent extracts of selected
medicinal plants was investigated. The different solvents plant extracts from
Annona squamosa, Pergularia daemia, Bauhinia racemose, Cissus
quadrangularis, and Albizia lebbeck were tested for their ability to inhibit
xanthine oxidase. The maximum xanthine oxidase enzyme inhibition was
found in Cissus quadrangularis chloroform extract (IC50 = 0.197 mg/ml),
whereas the lowest activity was recorded in Annona squamosa water extract
(IC50 = 0.672 mg/ml). The different solvent extracts of Pergularia daemia,
Bauhinia racemose, and Albizia lebbeck showed moderate xanthine oxidase
inhibitory activity. The ethanolic extract (83.72 mg/g) of Pergularia daemia
showed the maximum amount of phenolic content followed by the ethanolic
extract (77.11 mg/g) of Cissus quadrangularis.

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Published

2018-12-31

How to Cite

Dhole GA, & Bodke SS. (2018). Xanthine oxidase inhibition by using different extracts of selected medicinal plants . International Journal of Life Sciences, 6(4), 1069–1072. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/654

Issue

Vol. 6 No. 4 (2018): International Journal of Life Sciences

Section

Research Articles

License

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