Metabolite profile of false elder leaves (Peronema canescens Jack.) based on development levels
Keywords:
Metabolite profile, Leaf development, Peronema canescens Jack, (Sungkai, False Elder), GC-MSAbstract
At each stage of leaf development, the formation of compounds in the leaves will occur, thus allowing the chemical components in it to also experience changes, both the properties possessed by a plant and the quantity of metabolites it has. This study aims to determine the differences in metabolites and the abundance of metabolites of Sungkai or False Elder leaves (Peronema canescens Jack.) based on the level of leaf development with a non-target metabolomics analysis approach using GC-MS. Obtained metabolite compounds were acquired using a quantitative descriptive method. Obtained differences and abundance of detected metabolites. Sungkai young, mature, and old leaves show 17 types of metabolites. The abundance of each type of compound from each leaf development was different, and the total abundance of metabolite compounds was found in mature Sungkai leaves at 75.64%, followed by young Sungkai leaves at 71.55% and old Sungkai leaves at 51.27%. . The results show that there are unique compounds such as phenol, 2,6-dimethoxy-4-(2-propenyl)- and ursodeoxycholic acid which are detected which are known to have pharmacological effects as natural immunomodulators for the body
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Ahmad I and Ibrahim A (2015) Bioactivity of Methanol Extract and n-Hexane Fraction of Sungkai Leaves (Peronema canescens Jack.) Against Shrimp Larvae (Artemia salina Leach) (Bioaktivitas Ekstrak Metanol dan Fraksi n-Heksana Daun Sungkai (Peronema canescens Jack.) terhadap Larva Udang (Artemia salina Leach)). Jurnal Sains dan Kesehatan. 1(3) : 114–119. https://doi.org/10.25026/jsk.v1i3.27
Antari NPU, Dewi NPLY, Saputra IWM, Prascitasari NA, Arkhania NPAD, Aswindari NNZ, Juliari NPH, Andarista NKN, Kosalawa AAND, Jayanti NKA, Lestari MD and Sangging IGB (2021) Correlation Between Understanding of Covid-19 and Use of Supplements, Students of the Faculty of Pharmacy Mahasaraswati University Denpasar. (Korelasi Antara Pemahaman Covid-19 Dan Penggunaan Suplemen, Mahasiswa Fakultas Farmasi Universitas Mahasaraswati Denpasar). Jurnal Ilmiah Medicamento. 7(1) : 1–7. https://doi.org/10.36733/ medicamento.v7i1.1029
Baky MH, Shawky EM, Elgindi MR and Ibrahim HA (2021) Comparative Volatile Profiling of Ludwigia stolonifera Aerial Parts and Roots Using VSE-GC-MS/MS and Screening of Antioxidant and Metal Chelation Activities. ACS Omega. 6(38) : 24788–24794. https://doi.org/10.1021/acsomega.1c03627
Beschi DA, Appavoo MR and Wilsy I (2021) GC-MS Analysis, Collected From Kavalkinaru Area, Tirunelveli District, Tamil Nadu, India. European. Journal of Molecular and Clinical Medicine. 7 (11) : 4287–4292. https://ejmcm.com/ article6597.html
Cha BC (2017) Biological Activities of Ursi Fel’s Component Ursodeoxycholic Acid and Its Derivatives. Korean Journal of Pharmacognosy. 48(1) : 10–17. https://koreascience.kr/article/JAKO201714940711535.view?orgId=anpor&hide=breadcrumb,journalinfo
Hamzah H, Afandi AA and Suarni S (2021) Test of Inhibitory Power of Palm Oil (CPO), Garlic and Turmeric Against Several Types of Vibrio sp. (Uji Daya Hambat Minyak Sawit (CPO), Bawang Putih dan Kunyit Terhadap Beberapa Jenis Bakteri Vibrio sp.). Journal of Aquatropica Asia. 6(1) : https://doi.org/10.33019/aquatropica.v6i1.2461
Hanifah L and Kiptiyah K (2020) Potency of Kesambi (Scheichera oleosa) as Immunomodulator Candidate (Potensi Kesambi (Scheichera oleosa) Sebagai Kandidat Imunomodulator). Prosiding Seminar Nasional Biologi. 1(1): 119–126. http://103.55.216.56/index.php/psb/article/view/15659
Hidayah D and Kawuryan DL (2018) Effect of Ursodeoxycholic Acid on Total Bilirubin Levels in Neonates Patients with Cholestasis Due to Sepsis (Pengaruh Asam Ursodeoksikolat Terhadap Kadar Bilirubin Total pada Pasien Neonates dengan Kolestasis Akibat Sepsis). Jurnal Medika Moewardi. 7(2): 1–5. https://rsmoewardi. com /wp-content/uploads/2021/01/JURNALMEDIKA-MOEWARDI-2018-vol.7-no.2.pdf
Ibrahim A and Kuncoro H (2012) Identification of Secondary Metabolites and Antibacterial Activity of Sungkai Leaf Extract (Peronema canescens Jack.) Against Several Pathogenic Bacteria (Identifikasi Metabolit Sekunder dan Aktivitas Antibakteri Ekstrak Daun Sungkai (Peronema canescens Jack.) Terhadap Beberapa Bakteri Patogen). Journal of Tropical Pharmacy And Chemistry. 2(1) : 8-18. https://doi.org/10.25026/ jtpc.v2i1.43
Karunia SD, Supartono and Sumarni W (2017) Analysis of Antibacterial Properties of Srikaya (Annona squamosa L.) Seed Extract with Organic Solvents. (Analisis Sifat Antibakteri Ekstrak Biji Srikaya (Annona squamosa L.) Dengan Pelarut Organik). Indonesian Journal of Chemical Science. 6(1) : 56-60. https://doi.org/10.15294/ ijcs.v6i1.11288
Ningtyas PZ, Prihastanti E and Saptiningsih E (2012) Effect of Stephania hernandifolia Walp Leaf Sequence Combination. and Addition of Water Volume on Grass Jelly Quality and Syneresis during Storage. (Pengaruh Kombinasi Urutan Daun Stephania hernandifolia Walp. dan Penambahan Volume Air Terhadap Kualitas dan Sineresis Cincau selama Penyimpanan). Buletin Anatomi dan Fisiologi dh Sellula. 19(2): 20–31. https://doi.org/10.14710/ baf.v19i2.3860
Novitasari EA and Putri ZD (2016) Isolation and Identification of Saponins in Mahkota Dewa Leaf Extract by Maceration Method. (Isolasi and Identifikasi Saponin Pada Ekstrak Daun Mahkota Dewa Dengan Metode Maserasi). Jurnal Sains. 6(12): 10-13. https://journal.unigres.ac.id/index.php/Sains/article/view/577/450
Patil A and Jadhav V (2014) GC-MS Analysis of Bioactive Components from Methanol Leaf Extract of Toddalia asiatica (L.). International Journal of Pharmaceutical Sciences Review and Research. 29(1): 18–20. https://globalresearchonline.net/journalcontents/ v29-1/04.pdf
Putri MF, Fifendy M and Putri DH (2018) Diversity of Endophytic Bacteria in Young and Old Leaves of Andaleh (Morus macroura Miq.). (Diversitas Bakteri Endofit Pada Daun Muda dan Tua Tumbuhan Andaleh (Morus macroura Miq.)). Eksakta : Berkala Ilmiah Bidang MIPA. 19(1): 125–130. https://doi.org/10.24036/eksakta/vol19-iss01/122
Rahman A, Rengganis GP, Prayuni S and Novriyanti I (2021) The Effect of Infusion of Sungkai Leaves (Peronema canescens Jack.) on the Number of Leukocytes in Mice. (Pengaruh Pemberian Infusa Daun Sungkai (Peronema canescens Jack.) Terhadap Jumlah Leukosit Pada Mencit). Journal of Healthcare Technology and Medicine. 7(2): 614–620. https://doi.org/https://doi.org/10.33143/jhtm.v7i2.1574
Ramya B, Malarvili T and Velavan S (2015) GC-MS Analysis of Bioactive Compounds in Bryonopsis Laciniosa Fruit Extract. International Journal of Pharmaceutical Sciences and Research. 6(8): 3375. https://doi.org/10.13040/IJPSR.0975-8232.6(8).3375-79
Sumenda L (2011) Analysis of Chlorophyll Content of Mango (Mangifera indica L.) Leaves at Different Levels of Leaf Development. (Analisis Kandungan Klorofil Daun Mangga (Mangifera indica L.) pada Tingkat Perkembangan Daun yang Berbeda). Jurnal Bios Logos. 1(1):20–24. https://ejournal.unsrat.ac.id/index.php/bioslogos/article/view/372
Tinungki MM, Pontoh J and Fatimawali (2018) Analysis of Chemical Components at Various Developmental Levels of Langsat Parasite (Dendrophthoe pentandra (L.) Miq.) Leaves Using Gas Chromatography Method. (Analisis Komponen Kimia Pada Berbagai Tingkat Perkembangan Daun Benalu Langsat (Dendrophthoe pentandra (L.) Miq.) Menggunakan Metode Kromatografi Gas). Jurnal Ilmiah Farmasi. 7(4): 108–114. https://doi.org/10.35799/pha.7.2018.21433
Wati L, Ernalia Y and Haslinda L (2014) Relationship of Nutrition Knowledge, Family Income and Soil Transmitted Helminths Infestation with Chronic Energy Deficiency (KEK) in Pregnant Women in the Siak River Coastal Area, Pekanbaru. (Hubungan Pengetahuan Mengenai Gizi, Pendapatan Keluarga dan Infestasi Soil Transmitted Helminths dengan Kekurangan Energi Kronik (KEK) pada Ibu Hamil Di Daerah Pesisir Sungai Siak Pekanbaru). Jurnal Online Mahasiswa Fakultas Kedokteran Universitas Riau. 1(2): 1–10. https://jom.unri.ac.id/index.php/JOMFDOK/article/ view/2807
WHO (2020) Coronavirus Disease (COVID-19) Weekly Epidemiological Update and Weekly Operational Update. World Health Organization. https://www.who.int /emergencies/diseases/novel-coronavirus-2019/situation-reports
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