Preliminary phytochemical analysis and antimicrobial activity of Strychnos nux – vomica Linn. (Loganiaceae)

Authors

  • Vadivalagan A  Department of Botany, Chikkaiah Naicker College, Erode-638004, Tamil Nadu, India
  • Kannan R  Department of Botany, Chikkaiah Naicker College, Erode-638004, Tamil Nadu, India
  • V. Balasubramaniam PG and Research Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore-641029, Tamilnadu, India

Keywords:

Strychnos nux-vomica, phyto-constituents, antimicrobial activity

Abstract

Strychnosnux-vomica Linn. (Loganiaceae) traditionally used as curative purpose for various kinds of diseases. The different use of this plant as herbal remedy in Chinese medicine and described in the vedic literature of Indian system of medicine too. Pharmacologically active phytoconstituents of Strychnos nux-vomica are Strychnine and brucine major alkaloids which are used to treat central nervous stimulant. These constituents found to be poisonous when prescribed at high levels. The present analysis of the different polarity of the solvent petroleum ether, acetone and methanol was used to test for the presence of phytochemical constituents of the bark of S.nux-vomica. The study revealed the presence of alkaloids, saponins, glycosides, tannins, phenols and resins as major constituents of this plant. The Antimicrobial activity different extracts of S.nux vomica bark against Serratia marcescens, Escherichia coli (gram negative bacterial pathogens) and Penicillium notatum, Fusarium oxysporum (fungal pathogens) were showed decent zone of inhibition in methanol extract.

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IJLSCI_Vol. 7 No. 3 (2019): Internationl Journal of Life Sciences

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Published

2019-09-30

How to Cite

Vadivalagan A, Kannan R, & V. Balasubramaniam. (2019). Preliminary phytochemical analysis and antimicrobial activity of Strychnos nux – vomica Linn. (Loganiaceae). International Journal of Life Sciences, 7(3), 551–556. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/845

Issue

Vol. 7 No. 3 (2019): International Journal of Life Sciences

Section

Research Articles

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