Strategic reduction of Plasmodium falciparum infant mortality in Nigeria: Enhancing healthcare equity through medical drone delivery of the RTS,S/AS01 vaccine

Authors

  • Saumik Das Academies of Loudoun
  • Brian Wolfe Edgewood Jr/Sr High School
  • Varchas Kukreja Mission San Jose High School
  • Yubo Gao Abingdon School

Keywords:

Malaria, vaccine, global health, bioethics, health inequity, United Nations Sustainable Development Goals (UN SDGs), global sustainability

Abstract

Malaria has been known to be a fatal disease that can be transmitted through the exchange of blood and is carried by the plasmodium parasite. Nigeria is one of the countries in Africa that has suffered the most from malaria, with the region accounting for 95% of malaria cases and 96% of malaria deaths. Malaria is the leading cause of child and infant mortality in Nigeria, due to the many healthcare disparities and inadequate access to current treatments. We researched the distribution and transportation issues around inefficient road systems, and vaccine storage surrounding malaria treatment, using a case study of a Rwandan drug transportation startup known as Zipline. When investigating through an ethical lens, we focused on the concepts of priority setting for malaria cases in Nigeria, specifically infant health groups, and the ethical mass distribution of vaccines. By integrating self-assembled, automated, GPS-routed, electronic drones and optimizing the storage system, our research aimed to propose a cutting-edge, sustainable ethical solution for the distribution of the RTS, S/AS01 vaccine. This research shines light on how to effectively combat similar health crises via the usage of medical delivery drones for mass administration.

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References

Ackerman E (2022, February 28) In the air with Zipline’s medical delivery drones. IEEE Spectrum. https://spectrum.ieee.org/in-the-air-with-ziplines-medical-delivery-drones

Arora N, C Anbalagan L & Pannu AK (2022) Towards Eradication of Malaria: Is the WHO’s RTS,S/AS01 Vaccination Effective Enough? Risk Management and Healthcare Policy, 14, 1033–1039. Taylor & Francis Online. https://doi.org/10.2147/RMHP.S219294

CDC (2019) CDC - Malaria - Diagnosis & Treatment (United States) - Diagnosis (U.S.). CDC. https://www.cdc.gov/malaria/diagnosis_treatment/diagnosis.html

Datoo MS, Natama MH, Somé A, Traoré O, Rouamba T, Bellamy D, Yameogo P, Valia D, Tegneri M, Ouedraogo, F, Soma R, Sawadogo S, Sorgho F, Derra K, Rouamba E, Orindi B, Lopez FR, Flaxman A, Cappuccini F, & Kailath R (2021) Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: A randomized controlled trial. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(21)00943-0

Effiong FB, Makata VC, Elebesunu EE, Bassey EE, Salachi KI, Sagide MR, Abdulameed, HT, & Uwishema O (2022) Prospects of malaria vaccination in Nigeria: Anticipated challenges and lessons from previous vaccination campaigns. Annals of Medicine and Surgery, 81, 104385. https://doi.org/10.1016/j.amsu.2022.104385

Griffith EF, Schurer JM, Mawindo B, Kwibuka R, Turibyarive T & Amuguni JH (2023b) The Use of Drones to Deliver Rift Valley Fever Vaccines in Rwanda: Perceptions and Recommendations. Vaccines, 11(3), 605. https://doi.org/10.3390/vaccines11030605

Health in Nigeria. (2022, March 15). The Lancet. https://www.thelancet.com/infographics-do/nigeria

Jamrozik E, de la Fuente-Núñez V, Reis A, Ringwald P, & Selgelid MJ (2015) Ethical aspects of malaria control and research. Malaria Journal, 14. https://doi.org/10.1186/s12936-015-1042-3

Laurens MB (2019) RTS,S/AS01 Vaccine (MosquirixTM): an Overview. Human Vaccines & Immunotherapeutics, 16(3), 1–10. Taylor & Francis Online. https://doi.org/10.1080/21645515.2019.1669415

Maduka O (2018) End malaria for good: a review of current strategies and future novelties for malaria elimination in Nigeria. MalariaWorld Journal, 9, 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415072/#:~:text=Malaria%20control%20in%20Nigeria%

Malaria Fact Sheet. (2017) Www.health.ny.gov. https://www.health.ny.gov/diseases/communicable/malaria/fact_sheet.htm#:~:text=Malaria%20is%20spread%20by%20the

Mitchie S, Atkins L, & West R (2014) The behavior change wheel is a guide to designing interventions. Bream Silverback Publishing.

Ojo SO, Bailey DP, Brierley ML, Hewson DJ, & Chater AM (2019) Breaking barriers: Using the behavior change wheel to develop a tailored intervention to overcome workplace inhibitors to breaking up sitting time. BMC Public Health, 19(1). https://doi.org/10.1186/s12889-019-7468-8

UNICEF (2018) Malaria in Africa - UNICEF DATA. UNICEF DATA. https://data.unicef.org/topic/child-health/malaria/

WHO (2023, March 29). Malaria. Who.int; World Health Organization: WHO. https://www.who.int/news-room/fact-sheets/detail/malaria

Winskill P, Walker PG, Cibulskis RE, & Ghani AC (2019) Prioritizing the scale-up of interventions for malaria control and elimination. Malaria Journal, 18(1). https://doi.org/10.1186/s12936-019-2755-5

Zipline fact sheet - professional education. (n.d.). https://professionaleducation.blood.ca/sites/default/files/2023-04/Zipline_Fact_Sheet.pdf

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Published

2024-03-31

How to Cite

Das, S., Wolfe, B., Kukreja, V., & Gao, Y. (2024). Strategic reduction of Plasmodium falciparum infant mortality in Nigeria: Enhancing healthcare equity through medical drone delivery of the RTS,S/AS01 vaccine. International Journal of Life Sciences, 12(1), 21–27. Retrieved from https://ijlsci.in/ls/index.php/home/article/view/876