Optimizing the Biosynthesis of Selenium Nanoparticles from Sodium Selenite via Vibrio Natriegens as a Microbial Factory to Solve Semiconductor Shortages
Keywords:
Vibrio natriegens, Selenium Nanoparticle Biosynthesis, Sodium Selenite, SemiconductorAbstract
This research project aims to optimize the biosynthesis of selenium nanoparticles (SeNPs) using Vibrio natriegens as a microbial factory. SeNPs have shown great potential in various applications, such as biomedicine, electronics, and environmental remediation. Selenium is an essential trace element that plays a vital role in many biological processes, including antioxidant defense and immune system function. Selenium deficiency has been associated with various health problems, including cancer, cardiovascular disease, and thyroid dysfunction. SeNPs have emerged as a promising candidate for selenium supplementation due to their enhanced bioavailability and antioxidant activity. The Biosynthesis of SeNPs using microorganisms is an eco-friendly and cost-effective method. In this study, Vibrio natriegens, a fast-growing marine bacterium, was utilized for the biosynthesis of SeNPs from sodium selenite (Na2SeO3). The primary parameter affecting SeNP biosynthesis, the concentration of Na2SeO3, was optimized to maximize Selenium production while minimizing Na2SeO3 toxicity. The biosynthesis of SeNPs was monitored using UV-Vis spectrophotometry. The optimized conditions for SeNP biosynthesis were found to be 60 mM Na2SeO3. The optimized biosynthesis method presented in this study offers a potential avenue for the large-scale production of SeNPs using Vibrio natriegens as a microbial factory. The eco-friendly nature and low cost of this biosynthesis method make it an attractive alternative to conventional chemical synthesis methods.
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