GC-MS analysis of ethanolic extract of aerial parts of Cyperus scariosus R.Br.
Keywords:
Cyperus scariosus, aerial parts, GC-MS analysis, phytochemical compoundsAbstract
Cyperus scariosus R.Br. belongs to family Cyperaceae, distributed in and around rivers, waterfalls and other damp areas throughout India. The extracts of Cyperus scariosus have been frequently used as anti-hyperglycemic, hepato-protective, anti-nociceptive, anti-fungal, plant growth regulator, insecticidal and ovicidal agent, among other medicinal purposes. In the present investigation, the ethanolic extract of aerial parts including leaves, flowers and aerial stem of C. scariosus was analyzed by gas chromatography-mass spectrometry (GC–MS) to identify the important phytochemical constituents. The GC–MS analysis revealed the presence of 17 phytochemical compounds. The major compounds were identified as 2, 2,6-Trimethyl-4H-1,3-dioxin-4-one (65.73%), Trichloroacetic acid, 4-methylpentyl ester (7.98 %), 3-Methoxy-3-methyl-1-pentene (4.67%), 2-Propenoic acid, 2-(acetylamino)- (3.96%) , 1-Pentanol, 2-methyl- (3.35%) and 4-Dodecanol (3.08%).
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Alam MA, Jahan R, Rahman S, Das AK and Rahmatullah M (2011) Anti nociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus. Pakistan journal of pharmaceutical sciences, 24(1): 53-56.
Arshiya S, Khaleeq UR, Padmaja AR and Ateeq UR (2013) Cyperus scariosus Roxb a herb with unani traditional uses and pharmacological activity: a review World Journal of Pharmaceutical Research, 2(6): 2153-2162.
Chawda HM, Mandavia DR, Parmar PH, Baxi SN and Tripathi CR (2014) Hypolipidemic activity of a hydroalcoholic extract of Cyperus scariosus Linn. root in guinea pigs fed with a high cholesterol diet. Chinese journal of natural medicines, 12(11): 819-826.
Fan S, Chang J, Zong Y, Hu G and Jia J (2018) GC-MS analysis of the composition of the essential oil from Dendranthema indicum Var. Aromaticum using three extraction methods and two columns. Molecules (Basel, Switzerland), 23(3): 1-11
Gilani AH and Janbaz KH (1995) Studies on protective effect of Cyperus Scariosus extract on acetaminophen and CCl4-induced hepatotoxicity. General Pharmacology, 26 (3): 627-631.
Gilani AH, Janbaz KH, Zaman M, Lateef A, Tariq SR, Ahmad HR (1994) Hypotensive and spasmolytic activities of crude extract of Cyperus scariosus. Archives of Pharmacal Research, 17(3): 145-149.
Jani DK and Murthy AR ( 2012) An ayurvedic medicinal plant survey in new vallabh vidyanagar, Anand, Gujarat, India, International Multidisciplinary e- journal, 1: 95-104.
Kasana B, Sharma SK, Singh L, Mohapatra S and Singh T (2013) Cyperus scariosus: A potential medicinal herb. International Research Journal of Pharmacy 4 (6): 17–20.
Kavitha R. (2021) Phytochemical screening and GC-MS analysis of bioactive compounds present in ethanolic extracts of leaf and fruit of Trichosanthesis dioica Roxb. International Journal of Pharmaceutical Sciences and Research, 12(5):2755-2764.
Kirtikar KR and Basu BD (1918) Indian Medicinal Plants. Panina Office, Allahabad, pp.1355-1356.
Konappa N, Udayashankar AC, Krishnamurthy, S. et al. (2020) GC–MS analysis of phytoconstituents from Amomum nilgiricum and molecular docking interactions of bioactive serverogenin acetate with target proteins. Scientific Reports 10, 16438.
Lahariya AK and Rao JT (1979) In vitro antimicrobial studies of the essential oil of Cyperus scariosus and Ocimum basilicum. Indian Drugs, 16(7): 150-152.
Nadkarni AK (2009) Indian Materica Medica. Vol.1. Mumbai; Popular Prakashan Pvt Ltd: pp.211-2, 428-9.
Paz CA, Cerdeiras MP and Fernadez J (1995) Screening of Uruguayan medicinal plants for antimicrobial activity. Journal of Ethanopharmacology, 45(1): 67-70.
Ramesh S, Rao BM, Mahesh V, Prabhaker T, Swamy P, Nagaraju P (2012) Pharmacological study of anti-depressant like activity of Cyperus scariosus oil in mice. International Research Journal of Pharmaceutical and Applied Sciences, 2(5):139-142.
Razack S, Kumar KH, Nallamuthu I, Naika M and Khanum F (2015) Antioxidant, biomolecule oxidation protective activities of Nardostachys jatamansi DC and its phytochemical analysis by RP-HPLC and GC-MS. Antioxidants 4: 185–203.
Rishikesh M, Rahman SMM, Islam S and Rahman MM (2012) Phytochemical screening and in-vitro antimicrobial investigation of the methanolic extract of Centella asiatica leaves. International Journal of Pharmaceutical Science and Research, 3(9): 3323-3330.
Said HM (1982). Diseases of the liver: Greco-Arab concepts, Hamdard Foundation Press, Karachi, pp.120-121.
Satapute P, Murali K P, Kurjogi M and Jogaiah S (2019) Physiological adaptation and spectral annotation of Arsenic and Cadmium heavy metal-resistant and susceptible strain Pseudomonas taiwanensis. Environmental Pollution, 251: 555–563.
Sharma N, Singh S and Singh SK (2017) Development of Quality Control Parameters for Standardization of Cyperus scariosus R.Br. Roots. International Journal of Pharmacognosy and Phytochemical Research, 9(6): 840-845.
Srivastava RK, Singh A, Srivastava GP, Lehri A, Nirajan A, Tewari SK, Kumar K and Kumar S (2014) Chemical constituents and biological activities of promosing aromatic plant nagarmotha (Cyperus scariosus R. Br.): A Review. Proceedings of the National Academy of Sciences 80: 525–536.
Utreja D, Sharma P and Ekta (2015) Chemistry and biology of Cyperus scariosus: An overview. Current Chemical Biology, 9 (1): 2–9.
Watt G (1972) A Dictionary of the Economic Products of India. Cosmo Publications, Delhi, Vol. II, pp.687-88.
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