Antimicrobial activity of actinomycetes strain isolated from alkaline water of Lonar Lake.
Keywords:
Actinomycetes, Antimicrobial activity, antibiotics, soil sample, Staphylococcus aureusAbstract
The main focus of this study was to isolate some antibiotic producing actinomycetes strains from Halo alkaline water of Lonar Lake. Isolation of soil actinomycetes was done by culture-dependent methods and Furthermore, microscopic examination. Total of 17 actinomycetes strains were isolated from the alkaline water of Lonar Lake and screened for their anti-bacterial activity. They were evaluated for their inhibitory activities on four test microorganisms. Five actinomycetes isolate which exhibited antimicrobial activity against at least two of the test organisms and were characterized by conventional methods. The cultural characteristics of isolates were also studied in different culture media. The results indicated that two isolates were highly active against Staphylococcus aureus strains. Most of the isolates inhibited growth of the Gram-negative bacteria tested. These microorganisms may have capability to produce some of the most important medicines ever developed.
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