Synthesis and studies antimicrobial activity of 5-p-tolylthiocarbamido-1-naphthol
Keywords:
5-p-tolylthiocarbamido-1-naphthol (L4), pathogenic bacteria, antimicrobial activity, disc diffusion methodAbstract
Present research work deal with synthesis of 5-p-tolylthiocarbamido-1-naphtho and check their antimicrobial activity against four human pathogens. This molecule was synthesized by condensation of 5-amino-1-naphthol with p-tolyl isothiocynate in acetone medium. Recently here focus to assert antimicrobial activity of this molecule against gram positive and gram negative human pathogen bacteria such as E. coli, Proteus vulgaries, P. aeruginos and S. aureus. Comparatively L4 showed highly activity against E.Coli rather than remaining three pathogens. This antimicrobial activity relationship confirmed that this compound is a potential candidate for future drugs discovery and development.
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Copyright (c) 2021 Wadekar Ajay B, Bhade Dhammapal L
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